E2F8

Description		E2F transcription factor 8
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Placenta Development Sprouting Angiogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Cell Proliferation Negative Regulation Of Cytokinesis Positive Regulation Of DNA Endoreduplication Cell Cycle Comprising Mitosis Without Cytokinesis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Trophoblast Giant Cell Differentiation Chorionic Trophoblast Cell Differentiation Hepatocyte Differentiation
Pathways		TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: APP EWSR1 FHL3 LZTR1 TFCP2 ZDHHC17
Entrez ID		79733
HPRD ID		10981
Ensembl ID		ENSG00000129173
Uniprot IDs		A0AVK6
PDB IDs		4YO2
Enriched GO Terms of Interacting Partners?
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