TFR2

Description		transferrin receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cytoplasmic Vesicle HFE-transferrin Receptor Complex
	Molecular Function	Transferrin Receptor Activity Protein Binding Co-receptor Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Receptor-mediated Endocytosis Acute-phase Response Response To Iron Ion Transferrin Transport Positive Regulation Of Endocytosis Positive Regulation Of Transcription By RNA Polymerase II Iron Ion Homeostasis Cellular Response To Iron Ion Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Protein Maturation
Pathways		Transferrin endocytosis and recycling
Drugs
Diseases		Hemochromatosis (HFE); Juvenile hemochromatosis (JH)
GWAS		Hematocrit ( 27863252 28017375 19862010) Hematological parameters ( 19820697) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 28017375) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Iron status biomarkers ( 21208937) Iron status biomarkers (iron levels) ( 25352340) Iron status biomarkers (transferrin saturation) ( 25352340) Mean corpuscular hemoglobin ( 29403010 27863252 28017375) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 27863252 28017375 19862010) Platelet count ( 27863252) Plateletcrit ( 27863252) Red blood cell count ( 29403010 28453575 27863252 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 27863252 28957414) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		4 interacting genes: HFE PRKAR2B SOCS3 TF
Entrez ID		7036
HPRD ID		05282
Ensembl ID		ENSG00000106327
Uniprot IDs		Q9UP52
PDB IDs
Enriched GO Terms of Interacting Partners?
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