TBX2

Description		T-box transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Heart Looping Outflow Tract Septum Morphogenesis Outflow Tract Morphogenesis Endocardial Cushion Morphogenesis Cardiac Chamber Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Notch Signaling Pathway Central Nervous System Development Muscle Cell Fate Determination Cell Aging Regulation Of Heart Contraction Positive Regulation Of Cell Proliferation Embryonic Heart Tube Development Aorta Morphogenesis Atrioventricular Canal Development Embryonic Digit Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Camera-type Eye Morphogenesis Cardiac Muscle Tissue Development Roof Of Mouth Development Positive Regulation Of Cardiac Muscle Cell Proliferation Pharynx Development Developmental Growth Involved In Morphogenesis Mammary Placode Formation Cellular Senescence Negative Regulation Of Heart Looping Negative Regulation Of Cardiac Chamber Formation
Pathways
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Chloride levels ( 29403010) Chronic kidney disease ( 20383146) Circulating fibroblast growth factor 23 levels ( 30217807) Coronary artery disease ( 29212778) Creatinine levels ( 31015462 20383145) Diastolic blood pressure ( 27841878 27618447 27618448 30487518) Estimated glomerular filtration rate ( 31015462) Height ( 20881960 19893584 18391951) Hypertension ( 27618447 30487518) Mean arterial pressure ( 26390057 27618448 30487518) Potassium levels ( 29403010) Pulse pressure ( 27841878 27618447) Sitting height ratio ( 25865494) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Systolic blood pressure ( 27841878 28739976 27618447 27618448 30487518)
Interacting Genes		3 interacting genes: CEBPE LZTR1 NKX2-5
Entrez ID		6909
HPRD ID		02850
Ensembl ID		ENSG00000121068
Uniprot IDs		A0A024QZ86 Q13207
PDB IDs
Enriched GO Terms of Interacting Partners?
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