SPARC

Description		secreted protein acidic and cysteine rich
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GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Cytoplasm Mitochondrion Plasma Membrane Cell Surface Nuclear Matrix Platelet Alpha Granule Platelet Alpha Granule Membrane Platelet Alpha Granule Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Endocytic Vesicle Lumen Glutamatergic Synapse
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding Extracellular Matrix Binding
	Biological Process	Ossification Negative Regulation Of Endothelial Cell Proliferation Platelet Degranulation Receptor-mediated Endocytosis Heart Development Response To Gravity Response To Lead Ion Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Cell Morphogenesis Extracellular Matrix Organization Lung Development Response To Lipopolysaccharide Response To L-ascorbic Acid Response To Cytokine Wound Healing Response To Peptide Hormone Pigmentation Response To Ethanol Response To Cadmium Ion Inner Ear Development Anatomical Structure Development Regulation Of Synapse Organization Response To Glucocorticoid Response To CAMP Response To Calcium Ion Bone Development Cellular Response To Growth Factor Stimulus
Pathways		Platelet degranulation Nuclear signaling by ERBB4 ECM proteoglycans Scavenging by Class H Receptors
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS
Interacting Genes		22 interacting genes: COL13A1 COL1A1 COL1A2 COL2A1 COL3A1 COL5A1 CPEB2 CTSK FN1 HSPG2 PDGFA PDGFB PLAT PLG SDC2 TGFB1 TGM2 THBS1 UBQLN1 VEGFA XRCC6 ZNF579
Entrez ID		6678
HPRD ID		01631
Ensembl ID		ENSG00000113140
Uniprot IDs		P09486
PDB IDs		1BMO 1NUB 1SRA 2V53
Enriched GO Terms of Interacting Partners?
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