MLST8

Description		MTOR associated protein, LST8 homolog
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol TORC1 Complex TORC2 Complex
	Molecular Function	Protein Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Cell Cycle Arrest Regulation Of Macroautophagy Positive Regulation Of Actin Filament Polymerization TOR Signaling Positive Regulation Of TOR Signaling Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization TORC1 Signaling Regulation Of GTPase Activity Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Cellular Response To Heat
Pathways		PIP3 activates AKT signaling Macroautophagy mTOR signalling mTORC1-mediated signalling HSF1-dependent transactivation Energy dependent regulation of mTOR by LKB1-AMPK CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability TP53 Regulates Metabolic Genes Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Height ( 28552196)
Interacting Genes		7 interacting genes: A2M APPL2 ATXN1 EIF4EBP1 MTOR PRMT1 RPTOR
Entrez ID		64223
HPRD ID		17031
Ensembl ID		ENSG00000167965
Uniprot IDs		Q9BVC4
PDB IDs		4JSN 4JSP 4JSV 4JSX 4JT5 4JT6 5FLC 5H64 5WBU 5WBY 5ZCS 6BCU 6BCX 6SB0 6SB2
Enriched GO Terms of Interacting Partners?
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