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PTAFR
Description
platelet activating factor receptor
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Secretory Granule Membrane
Tertiary Granule Membrane
Molecular Function
Lipopolysaccharide Binding
Lipopolysaccharide Receptor Activity
G Protein-coupled Receptor Activity
Platelet Activating Factor Receptor Activity
Protein Binding
Phospholipid Binding
G Protein-coupled Purinergic Nucleotide Receptor Activity
Mitogen-activated Protein Kinase Binding
Biological Process
Cytokine Production
Regulation Of Transcription By RNA Polymerase II
Chemotaxis
Inflammatory Response
Immune Response
G Protein-coupled Receptor Signaling Pathway
Parturition
Response To Symbiotic Bacterium
Positive Regulation Of Phospholipase C Activity
Cytokine-mediated Signaling Pathway
Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Tumor Necrosis Factor Production
Inositol Trisphosphate Biosynthetic Process
G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway
Neutrophil Degranulation
Positive Regulation Of Neutrophil Degranulation
Transcytosis
Positive Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of Translation
Negative Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Smooth Muscle Cell Proliferation
Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of Inositol Phosphate Biosynthetic Process
Cellular Response To Gravity
Cellular Response To CAMP
Cellular Response To Fatty Acid
Response To Dexamethasone
Positive Regulation Of Blood Vessel Diameter
Positive Regulation Of Voltage-gated Chloride Channel Activity
Positive Regulation Of Leukocyte Tethering Or Rolling
Positive Regulation Of Sensory Perception Of Pain
Positive Regulation Of Transcytosis
Positive Regulation Of Maternal Process Involved In Parturition
Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction
Cellular Response To 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
Pathways
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interleukin-10 signaling
Neutrophil degranulation
Interferon gamma signaling
Drugs
Platelet Activating Factor
Etizolam
Rupatadine
Diseases
GWAS
Blond vs. brown/black hair color (
30531825
)
Interacting Genes
8 interacting genes:
ARR3
ARRB2
CALM1
GORAB
GTPBP3
RGS4
SPATA24
TYK2
Entrez ID
5724
HPRD ID
01422
Ensembl ID
ENSG00000169403
Uniprot IDs
A8K7N8
P25105
PDB IDs
2B0X
Enriched GO Terms of Interacting Partners
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