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DUSP22
Description
dual specificity phosphatase 22
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Filamentous Actin
Leading Edge Of Lamellipodium
Molecular Function
Protein Tyrosine Phosphatase Activity
Non-membrane Spanning Protein Tyrosine Phosphatase Activity
Protein Tyrosine/serine/threonine Phosphatase Activity
Protein Tyrosine Kinase Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of T Cell Mediated Immunity
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cell Migration
Peptidyl-tyrosine Dephosphorylation
Regulation Of Cell Proliferation
Positive Regulation Of JNK Cascade
Negative Regulation Of T Cell Receptor Signaling Pathway
Negative Regulation Of T Cell Activation
Negative Regulation Of Focal Adhesion Assembly
Cellular Response To Epidermal Growth Factor Stimulus
Negative Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity
Pathways
Drugs
Diseases
GWAS
Albumin-globulin ratio (
29403010
)
Alopecia areata (
25608926
)
Asthma (childhood onset) (
31036433
)
Crohn's disease (
26192919
)
Inflammatory bowel disease (
26192919
)
Male-pattern baldness (
28196072
)
Non-albumin protein levels (
29403010
)
Serum total protein level (
29403010
)
Takayasu arteritis (
30498034
)
Interacting Genes
5 interacting genes:
HOXA1
MAP2K4
MAP2K7
MAPK14
MAPK8
Entrez ID
56940
HPRD ID
13255
Ensembl ID
ENSG00000112679
Uniprot IDs
A0A384NLC8
Q9NRW4
PDB IDs
1WRM
4WOH
Enriched GO Terms of Interacting Partners
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