PDGFC

Description		platelet derived growth factor C
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Nucleus Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Cell Surface Extracellular Exosome
	Molecular Function	Platelet-derived Growth Factor Receptor Binding Protein Binding Growth Factor Activity Protein Homodimerization Activity Growth Factor Receptor Binding
	Biological Process	Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Central Nervous System Development Positive Regulation Of Cell Proliferation Animal Organ Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Cell Migration Positive Regulation Of Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Fibroblast Proliferation Digestive Tract Development Embryonic Organ Development Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Division Bone Development Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Amino Acid Stimulus Positive Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323) Fasting blood insulin ( 22581228) Fasting blood insulin (BMI interaction) ( 22581228) HDL cholesterol ( 30275531) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 30598549 28869591) Hypospadias ( 25108383) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Major depressive disorder ( 29317602) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978) Platelet count ( 27863252) Plateletcrit ( 27863252) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 30578418) Speech perception in dyslexia ( 19786962) Systolic blood pressure ( 30224653 30578418) Triglyceride levels x loop diuretics use interaction ( 31806883) Type 2 diabetes ( 30297969)
Interacting Genes		5 interacting genes: PDGFRA PLAT PLAU ST14 SUMO1
Entrez ID		56034
HPRD ID		10529
Ensembl ID		ENSG00000145431
Uniprot IDs		Q9NRA1
PDB IDs
Enriched GO Terms of Interacting Partners?
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