RIC8B

Description		RIC8 guanine nucleotide exchange factor B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell Cortex
	Molecular Function	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Height ( 31562340) Night sleep phenotypes ( 27126917) Severe influenza A (H1N1) infection ( 26379185) Social autistic-like traits ( 24133439) Triglyceride levels ( 29083408 28334899) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		3 interacting genes: GNAQ GNAS LRP1
Entrez ID		55188
HPRD ID		16452
Ensembl ID		ENSG00000111785
Uniprot IDs		A0A024RBG9 B7WPL0 Q9NVN3
PDB IDs
Enriched GO Terms of Interacting Partners?
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