GATAD2A

Description		GATA zinc finger domain containing 2A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm NuRD Complex Nuclear Speck
	Molecular Function	Protein Binding Zinc Ion Binding Protein Binding, Bridging Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Negative Regulation Of Transcription, DNA-templated
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
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Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Breast cancer ( 29059683) Height ( 25282103 31562340) Nonalcoholic fatty liver disease ( 29385134) Pulse pressure ( 30578418) Red cell distribution width ( 28957414) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia ( 25056061 29483656 23974872) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Strenuous sports or other exercises ( 29899525) Type 2 diabetes ( 28869590)
Interacting Genes		11 interacting genes: CREBBP H2AC20 H2BC21 H3C1 H4C1 KAT2B KRT40 MBD2 MBD3 PAK4 SPOP
Entrez ID		54815
HPRD ID		11741
Ensembl ID		ENSG00000167491
Uniprot IDs		A0A024R7K7 A0A024R7M6 Q86YP4
PDB IDs		2L2L
Enriched GO Terms of Interacting Partners?
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