PON1

Description		paraoxonase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space High-density Lipoprotein Particle Spherical High-density Lipoprotein Particle Intracellular Membrane-bounded Organelle Extracellular Exosome Blood Microparticle
	Molecular Function	Aryldialkylphosphatase Activity Arylesterase Activity Calcium Ion Binding Phospholipid Binding Protein Homodimerization Activity Acyl-L-homoserine-lactone Lactonohydrolase Activity
	Biological Process	Cholesterol Metabolic Process Response To Toxic Substance Positive Regulation Of Cholesterol Efflux Dephosphorylation Lipoxygenase Pathway Aromatic Compound Catabolic Process Response To Nutrient Levels Positive Regulation Of Transporter Activity Negative Regulation Of Plasma Lipoprotein Oxidation Carboxylic Acid Catabolic Process Organophosphate Catabolic Process Phosphatidylcholine Metabolic Process Positive Regulation Of Binding Response To Fatty Acid Response To Fluoride
Pathways		Synthesis of 5-eicosatetraenoic acids
Drugs		Cefazolin Zinc Copper
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Health literacy ( 31250787) Metabolite levels ( 23281178) Response to TNF antagonist treatment ( 18615156)
Interacting Genes		3 interacting genes: ALB APOA1 CLU
Entrez ID		5444
HPRD ID		01351
Ensembl ID		ENSG00000005421
Uniprot IDs		P27169
PDB IDs		1V04 1XHR
Enriched GO Terms of Interacting Partners?
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