PNMT

Description		phenylethanolamine N-methyltransferase
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Phenylethanolamine N-methyltransferase Activity N-methyltransferase Activity
	Biological Process	Methylation Epinephrine Biosynthetic Process Catecholamine Biosynthetic Process
Pathways		Catecholamine biosynthesis
Drugs		S-adenosyl-L-homocysteine 1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide 7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline 8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE (3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE (3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE [(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL (1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine (1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL
Diseases
GWAS		Alcohol consumption ( 31358974) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Bronchial hyperresponsiveness in asthma ( 27439200) Pancreatic ductal adenocarcinoma ( 30541042) Ulcerative colitis ( 20228799 21297633) Urinary metabolites ( 26352407)
Interacting Genes		2 interacting genes: TERF1 TERF2IP
Entrez ID		5409
HPRD ID		07176
Ensembl ID		ENSG00000141744
Uniprot IDs		A8MT87 P11086
PDB IDs		1HNN 1N7I 1N7J 1YZ3 2AN3 2AN4 2AN5 2G70 2G71 2G72 2G8N 2OBF 2ONY 2ONZ 2OPB 3HCA 3HCB 3HCC 3HCD 3HCE 3HCF 3KPJ 3KPU 3KPV 3KPW 3KPY 3KQM 3KQO 3KQP 3KQQ 3KQS 3KQT 3KQV 3KQW 3KQY 3KR0 3KR1 3KR2 4DM3 4MIK 4MQ4
Enriched GO Terms of Interacting Partners?
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