PECAM1

Description		platelet and endothelial cell adhesion molecule 1
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Integral Component Of Membrane Smooth Muscle Contractile Fiber Secretory Granule Membrane Platelet Alpha Granule Membrane Protein-containing Complex Cell-cell Contact Zone Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity
	Biological Process	Angiogenesis Endothelial Cell Morphogenesis Positive Regulation Of Protein Phosphorylation Platelet Degranulation Phagocytosis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Leukocyte Cell-cell Adhesion Signal Transduction Rho Protein Signal Transduction Cell Recognition Extracellular Matrix Organization Positive Regulation Of Cell Migration Monocyte Extravasation Wound Healing Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Neutrophil Degranulation Endothelial Cell Migration Positive Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Diapedesis Establishment Of Endothelial Barrier Bicellular Tight Junction Assembly Glomerular Endothelium Development Neutrophil Extravasation Endothelial Cell-matrix Adhesion Cell-cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		Platelet degranulation Cell surface interactions at the vascular wall PECAM1 interactions Integrin cell surface interactions Platelet sensitization by LDL Neutrophil degranulation
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Pulse pressure ( 27841878 30578418) Systolic blood pressure ( 27841878)
Interacting Genes		22 interacting genes: CD38 CSK CTNNB1 DSP EFNB2 FYN HCK INPP5D ITGA5 ITGB3 JUP LCK LYN PIK3R1 PLCG1 PRKCE PRPF40A PTPN11 PTPN6 SRC XRCC6 YES1
Entrez ID		5175
HPRD ID		01425
Ensembl ID		ENSG00000261371
Uniprot IDs		P16284
PDB IDs		2KY5 5C14 5GNI
Enriched GO Terms of Interacting Partners?
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