SIX6

Description		SIX homeobox 6
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Visual Perception Animal Organ Morphogenesis Negative Regulation Of Transcription, DNA-templated Anatomical Structure Development
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 22419738 29891935 25173105 29452408 22570617) Gut microbiota (bacterial taxa) ( 27723756) Height ( 20881960 25429064) Medication use (antiglaucoma preparations and miotics) ( 31015401) Menarche (age at onset) ( 25231870) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 25631615 31798171 28073927) Refractive error ( 23396134) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Urinary sodium excretion ( 31409800) Vertical cup-disc ratio ( 31798171 25241763 28073927)
Interacting Genes		3 interacting genes: GTF2A1L TLE1 TLE5
Entrez ID		4990
HPRD ID		07557
Ensembl ID		ENSG00000184302
Uniprot IDs		O95475 Q6P051
PDB IDs
Enriched GO Terms of Interacting Partners?
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