ATP2B1

Description		ATPase plasma membrane Ca2+ transporting 1
Image
GO Annotations	Cellular Component	Immunological Synapse Cell Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cell Junction Dendritic Spine Membrane Neuronal Cell Body Membrane Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Presynaptic Active Zone Membrane
	Molecular Function	Calcium-transporting ATPase Activity Protein Binding Calmodulin Binding ATP Binding Calcium Ion Transmembrane Transporter Activity ATPase Activity Cation-transporting ATPase Activity PDZ Domain Binding Metal Ion Binding Calcium-transporting ATPase Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Negative Regulation Of Cytokine Production Regulation Of Vascular Smooth Muscle Contraction Neural Retina Development Cellular Calcium Ion Homeostasis Brain Development Aging Regulation Of Blood Pressure Response To Cold Positive Regulation Of Bone Mineralization Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Calcium Ion Transport Cellular Response To Vitamin D Cellular Response To Corticosterone Stimulus Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Cellular Response To Insulin Stimulus Regulation Of Cardiac Conduction Calcium Ion Export Across Plasma Membrane
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Automobile speeding propensity ( 30643258) Biomedical quantitative traits ( 19396169) Blood pressure ( 24954895 21572416 24001895 21909110) Calcium levels ( 29403010) Chronotype ( 30696823) Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 22751097) Diastolic blood pressure ( 26390057 19430479 27841878 29403010 28739976 27618452 25249183 30487518) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure (long-term average) ( 28348047) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Diffusing capacity of carbon monoxide ( 30694715) Hypertension ( 31513605 31879980 19430479 25249183 28273873 30487518) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Magnesium levels ( 20700443) Mean arterial pressure ( 26390057 29403010 27618448 30487518) Mean arterial pressure (long-term average) ( 28348047) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Morning person ( 30696823) Myocardial infarction ( 26343387) Nonobstructive coronary artery disease ( 26534935) Pulse pressure ( 26390057 27841878 29403010 28739976 30487518 30578418) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 30224653 26390057 19430479 27841878 29403010 28739976 27618447 27618452 25249183 30487518 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure (long-term average) ( 28348047) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Total body bone mineral density ( 29304378)
Interacting Genes		5 interacting genes: CALM1 CSNK2A1 ERBIN PRKACA PRKCA
Entrez ID		490
HPRD ID		00158
Ensembl ID		ENSG00000070961
Uniprot IDs		A0A024RBC7 P20020
PDB IDs		6A69
Enriched GO Terms of Interacting Partners?
Tagcloud ?