NDUFS1

Description		NADH:ubiquinone oxidoreductase core subunit S1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Apoptotic Mitochondrial Changes Mitochondrial Respiratory Chain Complex I Assembly Cellular Respiration ATP Metabolic Process Regulation Of Mitochondrial Membrane Potential Reactive Oxygen Species Metabolic Process
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Body mass index ( 26426971) Chronotype ( 30696823) Frontotemporal dementia with GRN mutation ( 29724592) Morning person ( 30696823)
Interacting Genes		3 interacting genes: CASP3 KDM1A MDH2
Entrez ID		4719
HPRD ID		01145
Ensembl ID		ENSG00000023228
Uniprot IDs		E5KRK5 P28331
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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