MYH7

Description		myosin heavy chain 7
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GO Annotations	Cellular Component	Stress Fiber Muscle Myosin Complex Myosin Complex Myofibril Sarcomere Z Disc Myosin Filament
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Regulation Of Heart Rate Skeletal Muscle Contraction Muscle Contraction Striated Muscle Contraction Adult Heart Development Regulation Of The Force Of Skeletal Muscle Contraction Transition Between Fast And Slow Fiber Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction ATP Metabolic Process Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways
Drugs		4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Hypertrophic cardiomyopathy (HCM) Myosin storage myopathy (MSM); Hyaline body myopathy Scapuloperoneal myopathy (SPM) Dilated cardiomyopathy (DCM)
GWAS		Atrial fibrillation ( 30061737 29892015) Resting heart rate ( 27798624 20639392)
Interacting Genes		5 interacting genes: DISC1 KXD1 TEAD1 TEAD3 TEAD4
Entrez ID		4625
HPRD ID		01175
Ensembl ID		ENSG00000092054
Uniprot IDs		P12883
PDB IDs		1IK2 2FXM 2FXO 3DTP 4DB1 4P7H 4PA0 4XA1 4XA3 4XA4 4XA6 5CHX 5CJ0 5CJ1 5CJ4 5TBY 5WJ7 5WJB 5WLQ 5WLZ 5WME
Enriched GO Terms of Interacting Partners?
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