AGRN

Description		agrin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Golgi Lumen Cytosol Plasma Membrane Integral Component Of Membrane Cell Junction Lysosomal Lumen Synapse Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Dystroglycan Binding Structural Constituent Of Cytoskeleton Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Sialic Acid Binding Chondroitin Sulfate Binding Laminin Binding Heparan Sulfate Proteoglycan Binding
	Biological Process	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Cytoskeleton Organization Signal Transduction G Protein-coupled Acetylcholine Receptor Signaling Pathway Neuromuscular Junction Development Motor Neuron Axon Guidance Animal Organ Morphogenesis Tissue Development Dendrite Development Extracellular Matrix Organization Receptor Clustering Positive Regulation Of GTPase Activity Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Synaptic Growth At Neuromuscular Junction Positive Regulation Of Transcription By RNA Polymerase II Synapse Organization Positive Regulation Of Filopodium Assembly
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Integrin cell surface interactions Non-integrin membrane-ECM interactions ECM proteoglycans ECM proteoglycans Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS NCAM1 interactions Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport
Drugs
Diseases		Congenital myasthenic syndrome
GWAS
Interacting Genes		6 interacting genes: ATN1 ATXN7 CACNA1A DAG1 GFI1B UBC
Entrez ID		375790
HPRD ID		10550
Ensembl ID		ENSG00000188157
Uniprot IDs		O00468
PDB IDs
Enriched GO Terms of Interacting Partners?
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