ITPKB

Description		inositol-trisphosphate 3-kinase B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane
	Molecular Function	Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity
	Biological Process	MAPK Cascade Regulation Of Protein Phosphorylation Myeloid Cell Homeostasis Signal Transduction Cell Surface Receptor Signaling Pathway Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Negative Regulation Of Neutrophil Apoptotic Process Common Myeloid Progenitor Cell Proliferation Inositol Phosphate Metabolic Process Positive Thymic T Cell Selection Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation Cellular Response To Calcium Ion
Pathways		Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		5 interacting genes: CALM1 GOLGA2 PRKACA PRKCA PSME3
Entrez ID		3707
HPRD ID		00942
Ensembl ID		ENSG00000143772
Uniprot IDs		B2R9J0 P27987
PDB IDs
Enriched GO Terms of Interacting Partners?
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