IGFBP7

Description		insulin like growth factor binding protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Insulin-like Growth Factor Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Embryo Implantation Negative Regulation Of Cell Proliferation Response To Heat Response To Retinoic Acid Cellular Response To Hormone Stimulus Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Steroid Biosynthetic Process Response To Cortisol
Pathways		Senescence-Associated Secretory Phenotype (SASP) Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Insulin Human Insulin Pork
Diseases
GWAS		Age-related macular degeneration ( 21909106) Alcohol consumption (max-drinks) ( 29460428) Blood protein levels ( 30072576 29875488 28240269) Brain volume in infants (grey matter) ( 28763065) Congenital heart disease (maternal effect) ( 28468790) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 28869591) Hyperemesis gravidarum ( 29563502) Severity of nausea and vomiting of pregnancy ( 29563502)
Interacting Genes		11 interacting genes: CCL21 CCL5 CHMP3 CXCL10 IGF1 IGF2 INHBA INS RBBP8 SDC1 VEGFA
Entrez ID		3490
HPRD ID		04183
Ensembl ID		ENSG00000163453
Uniprot IDs		Q16270
PDB IDs
Enriched GO Terms of Interacting Partners?
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