NCKAP1L

Description		NCK associated protein 1 like
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Secretory Granule Membrane SCAR Complex Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Protein Kinase Activator Activity Protein-containing Complex Binding Rac GTPase Binding
	Biological Process	Cell Morphogenesis B Cell Homeostasis Myeloid Cell Homeostasis Chemotaxis Cell Migration Maintenance Of Cell Polarity Cell Projection Assembly Neutrophil Chemotaxis Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Positive Regulation Of B Cell Proliferation Activation Of Protein Kinase Activity Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Positive Regulation Of Cell Adhesion Mediated By Integrin Erythrocyte Homeostasis Negative Regulation Of Myosin-light-chain-phosphatase Activity Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Response To Drug T Cell Homeostasis Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of GTPase Activity Positive Regulation Of B Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Erythrocyte Development B Cell Receptor Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Protein-containing Complex Assembly Actin Polymerization-dependent Cell Motility Positive Regulation Of Neutrophil Chemotaxis
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: GAS7 PRPF40A
Entrez ID		3071
HPRD ID		00781
Ensembl ID		ENSG00000123338
Uniprot IDs		P55160
PDB IDs
Enriched GO Terms of Interacting Partners?
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