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H2AC8
Description
H2A clustered histone 8
Image
GO Annotations
Cellular Component
Nucleosome
Nuclear Chromatin
Nucleus
Extracellular Exosome
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Biological Process
Chromatin Organization
Chromatin Silencing
Negative Regulation Of Cell Proliferation
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
UCH proteinases
Ub-specific processing proteases
Metalloprotease DUBs
Deposition of new CENPA-containing nucleosomes at the centromere
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes
2 interacting genes:
EID1
NAP1L4
Entrez ID
3012
HPRD ID
04152
Ensembl ID
ENSG00000277075
Uniprot IDs
P04908
Q08AJ9
PDB IDs
2CV5
2RVQ
3A6N
3AFA
3AN2
3AV1
3AV2
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3W96
3W97
3W98
3W99
3WKJ
3WTP
3X1S
3X1V
4YM5
4YM6
4Z5T
5AV5
5AV6
5AV8
5AV9
5AVB
5AVC
5AY8
5B0Y
5B0Z
5B24
5B2I
5B2J
5B31
5B32
5B40
5CPI
5CPJ
5CPK
5GSE
5GTC
5GXQ
5JRG
5X7X
5XF3
5XF4
5XF5
5Y0C
5Y0D
5Z23
5ZBX
6A5L
6A5O
6A5P
6A5R
6A5T
6A5U
6ACL
6AEE
6BUZ
6E0C
6E0P
6HKT
6HTS
6INQ
6IQ4
6IR9
6J4W
6J4X
6J4Y
6J4Z
6J50
6J51
6JR0
6JR1
6O1D
6R8Y
6R8Z
6R90
6R91
6R92
6R93
6R94
Enriched GO Terms of Interacting Partners
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