GPX4

Description		glutathione peroxidase 4
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Mitochondrion Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	Peroxidase Activity Glutathione Peroxidase Activity Protein Binding Selenium Binding Identical Protein Binding Phospholipid-hydroperoxide Glutathione Peroxidase Activity
	Biological Process	Chromatin Organization Phospholipid Metabolic Process Glutathione Metabolic Process Response To Oxidative Stress Multicellular Organism Development Spermatogenesis Aging Lipoxygenase Pathway Response To Estradiol Long-chain Fatty Acid Biosynthetic Process Regulation Of Inflammatory Response Protein Polymerization Oxidation-reduction Process Cellular Oxidant Detoxification Negative Regulation Of Ferroptosis
Pathways		Synthesis of 5-eicosatetraenoic acids Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of 15-eicosatetraenoic acid derivatives
Drugs		Glutathione
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Asthma (childhood onset) ( 31036433) Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908 21102463 23128233) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Inflammatory bowel disease ( 28067908) Keratinocyte cancer (MTAG) ( 31174203) Nasal polyps ( 30643255) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		3 interacting genes: MAPK13 PARK7 PRDX6
Entrez ID		2879
HPRD ID		11819
Ensembl ID		ENSG00000167468
Uniprot IDs		P36969 Q6PI42
PDB IDs		2GS3 2OBI 5H5Q 5H5R 5H5S 6ELW
Enriched GO Terms of Interacting Partners?
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