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MLH3

Description mutL homolog 3
Image No pdb structure
GO Annotations Cellular Component
  • Synaptonemal Complex
  • Male Germ Cell Nucleus
  • Nucleus
  • Nucleoplasm
  • Chiasma
  • Mismatch Repair Complex
Molecular Function
  • Chromatin Binding
  • Satellite DNA Binding
  • Protein Binding
  • ATP Binding
  • ATPase Activity
  • Centromeric DNA Binding
  • Mismatched DNA Binding
Biological Process
  • Mismatch Repair
  • Synaptonemal Complex Assembly
  • Reciprocal Meiotic Recombination
  • Male Meiotic Nuclear Division
  • Female Meiosis I
  • Protein Localization
Pathways
  • Meiotic recombination
Drugs
Diseases
  • Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS
  • Inflammatory bowel disease ( 23128233)
  • Mood instability ( 29187730)
Interacting Genes 4 interacting genes: AR MLH1 MSH4 ZDHHC17
Entrez ID 27030
HPRD ID 05094
Ensembl ID ENSG00000119684
Uniprot IDs Q2M1Z1 Q9UHC1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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