FBXW8

Description		F-box and WD repeat domain containing 8
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol SCF Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm 3M Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Polyubiquitination Golgi Organization Cell Proliferation Protein Ubiquitination Post-translational Protein Modification Positive Regulation Of Dendrite Morphogenesis Spongiotrophoblast Layer Development Labyrinthine Layer Blood Vessel Development Positive Regulation Of Transcription Factor Catabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain structure ( 22504417) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) HATA volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Marginal zone lymphoma or rheumatoid arthritis ( 31407831) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459)
Interacting Genes		6 interacting genes: CUL7 IRS1 MYC RBX1 SKP1 UBE2D3
Entrez ID		26259
HPRD ID		16427
Ensembl ID		ENSG00000174989
Uniprot IDs		Q8N3Y1
PDB IDs
Enriched GO Terms of Interacting Partners?
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