ABCA12

Description		ATP binding cassette subfamily A member 12
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Epidermal Lamellar Body
	Molecular Function	Signaling Receptor Binding Lipid Transporter Activity Protein Binding ATP Binding ATPase Activity Lipid-transporting ATPase Activity Apolipoprotein A-I Receptor Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Lipid Transport Positive Regulation Of Cholesterol Efflux Cellular Homeostasis Keratinization Secretion By Cell Phospholipid Efflux Ceramide Transport Surfactant Homeostasis Regulated Exocytosis Lung Alveolus Development Transmembrane Transport Lipid Homeostasis Establishment Of Skin Barrier Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways		ABC transporters in lipid homeostasis Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE) Harlequin ichthyosis
GWAS
Interacting Genes		1 interacting genes: MTDH
Entrez ID		26154
HPRD ID		07416
Ensembl ID		ENSG00000144452
Uniprot IDs		B3KVV3 Q86UK0
PDB IDs
Enriched GO Terms of Interacting Partners?
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