IL27

Description		interleukin 27
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Cytosol
	Molecular Function	Signaling Receptor Binding Cytokine Activity Protein Binding Interleukin-27 Receptor Binding
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Inflammatory Response Response To Bacterium Regulation Of T Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process Innate Immune Response Regulation Of T-helper 1 Cell Differentiation Interleukin-27-mediated Signaling Pathway
Pathways		Interleukin-27 signaling Interleukin-27 signaling
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Ankylosing spondylitis ( 23749187) Blood protein levels ( 29875488) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062 29273807) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic obstructive pulmonary disease ( 28166215) Crohn's disease ( 30500874 28067908 21102463) Extremely high intelligence ( 29520040) FEV1 ( 30804560) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Lung function (FVC) ( 30804560) Type 1 diabetes ( 21829393 25751624 19430480)
Interacting Genes		1 interacting genes: IL27RA
Entrez ID		246778
HPRD ID		16307
Ensembl ID		ENSG00000197272
Uniprot IDs		Q8NEV9
PDB IDs
Enriched GO Terms of Interacting Partners?
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