PANX1

Description		pannexin 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Membrane Integral Component Of Membrane Bleb Protein-containing Complex
	Molecular Function	Protease Binding Signaling Receptor Binding Structural Molecule Activity Calcium Channel Activity Wide Pore Channel Activity Leak Channel Activity Ion Channel Binding Actin Filament Binding Gap Junction Hemi-channel Activity Scaffold Protein Binding
	Biological Process	Response To Ischemia Cation Transport Calcium Ion Transport Cell-cell Signaling Response To ATP Positive Regulation Of Interleukin-1 Alpha Secretion Positive Regulation Of Interleukin-1 Beta Secretion Calcium Ion Transmembrane Transport
Pathways		Electric Transmission Across Gap Junctions The NLRP3 inflammasome
Drugs		Probenecid
Diseases
GWAS		Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010) Medication use (thyroid preparations) ( 31015401) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		2 interacting genes: GNAS P2RX7
Entrez ID		24145
HPRD ID		10526
Ensembl ID		ENSG00000110218
Uniprot IDs		A0A024R397 Q96RD7
PDB IDs
Enriched GO Terms of Interacting Partners?
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