LPAR1

Description		lysophosphatidic acid receptor 1
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GO Annotations	Cellular Component	Cell Endosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endocytic Vesicle Neuronal Cell Body Dendritic Spine Dendritic Shaft
	Molecular Function	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding Lysophosphatidic Acid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Activation Of MAPK Activity G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cell Shape Negative Regulation Of Neuron Projection Development Oligodendrocyte Development Cerebellum Development Optic Nerve Development Corpus Callosum Development Bleb Assembly Positive Regulation Of Rho Protein Signal Transduction Myelination Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Stress Fiber Assembly Cell Chemotaxis Positive Regulation Of Dendritic Spine Development Cellular Response To Oxygen Levels Positive Regulation Of Smooth Muscle Cell Chemotaxis Cellular Response To 1-oleoyl-sn-glycerol 3-phosphate
Pathways		G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Central corneal thickness ( 31798171 29760442 30894546) Corneal structure ( 23291589) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Height ( 20881960 25282103 31562340) Monocyte count ( 28193307 29403010) Neutrophil percentage of granulocytes ( 27863252) Offspring birth weight ( 31043758) Post bronchodilator FEV1 in COPD ( 26634245) Pursuit maintenance gain ( 29064472) Sum eosinophil basophil counts ( 27863252) White blood cell count (monocyte) ( 28158719)
Interacting Genes		6 interacting genes: ARHGEF11 ARHGEF12 GIPC1 GNAI3 KRAS SLC9A3R2
Entrez ID		1902
HPRD ID		03790
Ensembl ID		ENSG00000198121
Uniprot IDs		Q5VZX0 Q92633
PDB IDs		4Z34 4Z35 4Z36
Enriched GO Terms of Interacting Partners?
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