AGXT

Description		alanine--glyoxylate and serine--pyruvate aminotransferase
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GO Annotations	Cellular Component	Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Serine-pyruvate Transaminase Activity Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Pyridoxal Phosphate Binding Identical Protein Binding Protein Homodimerization Activity Protein Self-association
	Biological Process	Protein Targeting To Peroxisome Notch Signaling Pathway Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process L-alanine Catabolic Process Pyruvate Biosynthetic Process Glyoxylate Metabolic Process Oxalic Acid Secretion Response To Glucocorticoid Response To CAMP
Pathways		Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs		Pyridoxal Phosphate Serine Glycine L-Alanine Aminooxyacetic acid N'-Pyridoxyl-Lysine-5'-Monophosphate 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases		Primary hyperoxaluria (HP)
GWAS		Blood metabolite levels ( 24816252) Height ( 25282103 31562340) Urinary metabolites ( 26352407)
Interacting Genes		4 interacting genes: ACAT1 GLP1R PEX5 SNCAIP
Entrez ID		189
HPRD ID		05048
Ensembl ID		ENSG00000172482
Uniprot IDs		P21549
PDB IDs		1H0C 1J04 2YOB 3R9A 4CBR 4CBS 4I8A 4KXK 4KYO 5F9S 5HHY 5LUC 5OFY 5OG0
Enriched GO Terms of Interacting Partners?
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