SLC26A3

Description		solute carrier family 26 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane Sperm Midpiece
	Molecular Function	DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transporter Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Anion:anion Antiporter Activity Oxalate Transmembrane Transporter Activity
	Biological Process	Regulation Of Transcription, DNA-templated Ion Transport Anion Transport Excretion Bicarbonate Transport Oxalate Transport Sperm Capacitation Intracellular PH Elevation Membrane Hyperpolarization Cellular Response To CAMP Sulfate Transmembrane Transport Chloride Transmembrane Transport
Pathways		Multifunctional anion exchangers Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1)
Drugs
Diseases
GWAS		Behavioural changes in frontotemporal lobe dementia ( 29724592) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 19915573 28067908 19122664) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: SLC9A3R1 SLC9A3R2
Entrez ID		1811
HPRD ID		00544
Ensembl ID		ENSG00000091138
Uniprot IDs		P40879
PDB IDs
Enriched GO Terms of Interacting Partners?
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