NQO1

Description		NAD(P)H quinone dehydrogenase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Dendrite Neuronal Cell Body Synapse
	Molecular Function	RNA Binding NAD(P)H Dehydrogenase (quinone) Activity Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Superoxide Dismutase Activity Protein Binding Oxidoreductase Activity Identical Protein Binding
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress Synaptic Transmission, Cholinergic Aging Response To Nutrient Response To Toxic Substance Removal Of Superoxide Radicals Electron Transport Chain Response To Estradiol Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Neuron Apoptotic Process Cell Redox Homeostasis Response To Ethanol Response To Electrical Stimulus Cellular Response To Hydrogen Peroxide Cellular Response To Metal Ion Response To Nitrogen Compound Response To Hydrogen Sulfide
Pathways		Regulation of ornithine decarboxylase (ODC)
Drugs		Menadione Dicoumarol Duroquinone 3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol 5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione Cibacron Blue Flavin adenine dinucleotide 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione RH-1 Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Blood osmolality (transformed sodium) ( 28360221) Blood protein levels ( 30072576 29875488) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body mass index ( 26426971) Estimated glomerular filtration rate ( 31015462) Medication use (HMG CoA reductase inhibitors) ( 31015401) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		7 interacting genes: DNAJB1 HIF1A HSPA1A ING1 STUB1 TP53 UBE2D1
Entrez ID		1728
HPRD ID		00518
Ensembl ID		ENSG00000181019
Uniprot IDs		B4DLR8 P15559
PDB IDs		1D4A 1DXO 1GG5 1H66 1H69 1KBO 1KBQ 1QBG 2F1O 3JSX 4CET 4CF6 5A4K 5EA2 5EAI 5FUQ 6FY4
Enriched GO Terms of Interacting Partners?
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