HMGB4

Description		high mobility group box 4
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding Transcription Factor Binding DNA Binding, Bending
	Biological Process	Activation Of Innate Immune Response DNA Recombination Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Signaling Receptor Activity Positive Regulation Of Autophagy Developmental Process Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Interleukin-1 Secretion Positive Regulation Of Interleukin-1 Beta Secretion Cell Chemotaxis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Interferon-alpha Secretion
Pathways
Drugs
Diseases
GWAS		Depressive symptoms (SSRI exposure interaction) ( 25649181)
Interacting Genes		3 interacting genes: APP CEP70 KRTAP12-4
Entrez ID		127540
HPRD ID		14038
Ensembl ID		ENSG00000176256
Uniprot IDs		Q8WW32
PDB IDs
Enriched GO Terms of Interacting Partners?
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