CHRNA3

Description cholinergic receptor nicotinic alpha 3 subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Chronic bronchitis and chronic obstructive pulmonary disease ( 25241909)
  • Chronic obstructive pulmonary disease ( 22080838 30804561 19300482 25101718 20173748)
  • Chronic obstructive pulmonary disease (moderate to severe) ( 24621683)
  • Chronic obstructive pulmonary disease (severe) ( 24621683)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Cotinine levels in smokers with chronic obstructive pulmonary disease ( 29631575)
  • Current cigarettes per day in chronic obstructive pulmonary disease ( 29767774)
  • Dentures ( 31235808)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Emphysema distribution in smoking ( 27669027)
  • Emphysema imaging phenotypes ( 26030696)
  • Exhaled carbon monoxide levels ( 25072098)
  • Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575)
  • Familial lung cancer ( 29924316)
  • Local histogram emphysema pattern ( 25006744)
  • Lung adenocarcinoma ( 19836008)
  • Lung cancer ( 18385676 18385738 19654303 18780872 30104567)
  • Lung cancer in ever smokers ( 30104567)
  • Lung function (FEV1/FVC) ( 31453325)
  • Lung function (FEV1/FVC) variance ( 31453325)
  • Nicotine dependence ( 18385739 26440539)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity-related traits ( 23251661)
  • Parental lifespan ( 29030599)
  • Parental longevity (combined parental attained age, Martingale residuals) ( 29227965)
  • Parental longevity (father's attained age) ( 29227965)
  • Parental longevity (mother's attained age) ( 29227965)
  • Peripheral artery disease ( 31285632)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1 in COPD ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Pre bronchodilator FEV1 ( 26634245)
  • Pre bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary artery enlargement and chronic obstructive pulmonary disease ( 25101718)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Serum albumin level ( 23022100)
  • Smoking behavior ( 20418889 20418890)
  • Smoking behaviour (cigarettes smoked per day) ( 31089300 30617275)
  • Smoking status (heavy vs light) ( 28520984)
  • Squamous cell lung carcinoma ( 28604730)
Interacting Genes 3 interacting genes: CHRNB4 ETFA UBQLN1
Entrez ID 1136
HPRD ID 07511
Ensembl ID ENSG00000080644
Uniprot IDs P32297
PDB IDs 4ZK4 5SYO 5TVC 6PV7 6PV8
Enriched GO Terms of Interacting Partners?
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