SPTLC1

Description		serine palmitoyltransferase long chain base subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Serine C-palmitoyltransferase Complex SPOTS Complex
	Molecular Function	Serine C-palmitoyltransferase Activity Protein Binding Pyridoxal Phosphate Binding
	Biological Process	Sphingolipid Metabolic Process Sphingomyelin Biosynthetic Process Sphingolipid Biosynthetic Process Sphinganine Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Positive Regulation Of Lipophagy Regulation Of Fat Cell Apoptotic Process
Pathways		Sphingolipid de novo biosynthesis
Drugs		Pyridoxal Phosphate Serine
Diseases
GWAS		Bipolar disorder and schizophrenia ( 22688191) Left inferior lateral ventricle volume (Cerebrospinal fluid biomarker status interaction) ( 25140149)
Interacting Genes		3 interacting genes: ABCA1 GTF2IRD1 SPTLC2
Entrez ID		10558
HPRD ID		05754
Ensembl ID		ENSG00000090054
Uniprot IDs		A0A024R277 O15269 Q6NUL7
PDB IDs
Enriched GO Terms of Interacting Partners?
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